Naujosios versijos projektavimo darbai prasidėjo dar 2004 metais, po patvirtintos plėtros programos 2003 metais. Koncepcinį modelį parengė Thomas Stopka 2005 m. Po subtilybių ir inžinerinių pakeitimų galutinės projekto specifikacija buvo patvirtinta 2006 m., bet darbai sustojo. W212 eksterjero stilius bei tam tikri elementai yra paimti iš praėjusių W204 C-klasės ir W221 S-klasės variantų , kurie atitinkamai pristatyti 2002 ir 2003 metais. Galinių ratų arkų dizaino koncepcija yra skirta priminti istorinių 1950 metų Mercedes modelius.
Rinkoje yra siūloma be sedano, papildomos kabrioleto, universalo, coupé versijos. O taip pat ir specialios Mercedes Benz W212 laidos, tokios kaip E63 AMG; E-Guard, E250 Blue TEC. Pasiūlyta galimybė rinktis automatinę arba mechaninę pavarų dėžę, artitinkamai 6-grečių, bei 5 greičių su 7G-Tronic Plus. Automobilio variklis gali būti benzininis arba dyzelinis.
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| Modelis | Metai | Variklis | Galia | Sukimo momentas | 0–100 km/h | Kuro naudojimas (ES norma) |
|---|---|---|---|---|---|---|
| Benzininiai varikliai | ||||||
| E 200 CGI BlueEFFICIENCY 212.048 | 2010- | 1,796 cc (1.796 L; 109.6 cu in) turbocharged I4 M 271 DE 18 AL | 184 PS (135 kW; 181 hp) | 270 N·m (200 lb·ft) | 8 sec | 4.850 L/100 km (48.50 mpg-US) |
| E 250 CGI BlueEFFICIENCY | 2010- | 1,796 cc (1.796 L; 109.6 cu in) turbocharged I4 M 271 DE 18 AL | 204 PS (150 kW; 201 hp) | 310 N·m (230 lb·ft) | 7.4 sec | 5.788 L/100 km (40.64 mpg-US) |
| E 300 | 2009-2011 | 2,996 cc (2.996 L; 182.8 cu in) V6 M 272 KE 30 | 231 PS (170 kW; 228 hp) | 300 N·m (220 lb·ft) | 7.4 sec | 4.500 L/100 km (52.27 mpg-US) |
| E 300 BlueEFFICIENCY | 2011- | 2,996 cc (2.996 L; 182.8 cu in) V6 M 276 DE 35 red. | 252 PS (185 kW; 249 hp) | 340 N·m (250 lb·ft) | 7.1 sec | 4.500 L/100 km (52.27 mpg-US) |
| E 300 4MATIC | 2011- | 2,996 cc (2.996 L; 182.8 cu in) V6 M 276 DE 35 red. | 252 PS (185 kW; 249 hp) | 300 N·m (220 lb·ft) | 7.4 sec | 4.500 L/100 km (52.27 mpg-US) |
| E 350 CGI BlueEFFICIENCY | 2009-2011 | 3,498 cc (3.498 L; 213.5 cu in) V6 M 272 DE 35 | 292 PS (215 kW; 288 hp) | 365 N·m (269 lb·ft) | 6.8 sec | 4.780 L/100 km (49.21 mpg-US) |
| E 350 4MATIC | 2009-2011 | 3,498 cc (3.498 L; 213.5 cu in) V6 M 272 KE 35 | 272 PS (200 kW; 268 hp)@6000 | 350 N·m (260 lb·ft)@2400-5000 | 6.5 sec | 5.844 L/100 km (40.25 mpg-US) |
| E 350 BlueEFFICIENCY | 2011- | 3,498 cc (3.498 L; 213.5 cu in) V6 M 276 DE 35 | 306 PS (225 kW; 302 hp) | 370 N·m (270 lb·ft) | 6.3 sec | 4.780 L/100 km (49.21 mpg-US) |
| E 350 4MATIC BlueEFFICIENCY | 2011- | 3,498 cc (3.498 L; 213.5 cu in) V6 M 276 DE 35 | 306 PS (225 kW; 302 hp)@6000 | 370 N·m (270 lb·ft)@2400-5000 | 6.6 sec | 5.844 L/100 km (40.25 mpg-US) |
| E 400 HYBRID | 2012- | 3,498 cc (3.498 L; 213.5 cu in) V6 M 276 DE 35 + el. motor | 331 PS (243 kW; 326 hp)@- | 620 N·m (460 lb·ft)@- | - sec | 5.844 L/100 km (40.25 mpg-US) |
| E 500 | 2009- | 5,461 cc (5.461 L; 333.3 cu in) V8 M 273 KE 55 | 388 PS (285 kW; 383 hp) @6000 | 530 N·m (390 lb·ft)@2800-4800 | 5.2 sec | 19.000 L/100 km (12.380 mpg-US) |
| E 500 4MATIC | 2009- | 4,663 cc (4.663 L; 284.6 cu in) V8 M 273 KE 55 | 388 PS (285 kW; 383 hp) @6000 | 530 N·m (390 lb·ft)@2800-4800 | 5.4 sec | 21.000 L/100 km (11.201 mpg-US) |
| E 500 BlueEFFICIENCY | 2011- | 4,663 cc (4.663 L; 284.6 cu in) twin-turbo V8 M 278 DE 46 AL red. | 408 PS (300 kW; 402 hp) @5250 | 600 N·m (440 lb·ft)@1600-4750 | 5.2 sec | 19.000 L/100 km (12.380 mpg-US) |
| E 500 4MATIC BlueEFFICIENCY | 2011- | 4,663 cc (4.663 L; 284.6 cu in) twin-turbo V8 M 278 DE 46 AL red. | 408 PS (300 kW; 402 hp) @5250 | 600 N·m (440 lb·ft)@1600-4750 | 5.2 sec | 19.000 L/100 km (12.380 mpg-US) |
| E 63 AMG | 2009–2011 | 6,208 cc (6.208 L; 378.8 cu in) M156 V8 M 156 E 63 | 525 PS (386 kW; 518 hp)@6800 | 630 N·m (460 lb·ft)@5200 | 4.5 sec | 9.8 L/100 km (24 mpg-US) |
| E 63 AMG | 2011- | 5,461 cc (5.461 L; 333.3 cu in) M157 twin-turbo V8 M 157 DE 55 AL | 525 PS (386 kW; 518 hp)@5250-5750 | 700 N·m (520 lb·ft)@1750–5000 | 4.3 sec | 21.2000 L/100 km (11.0950 mpg-US) |
| E 63 AMG Performance package | 2011- | 5,461 cc (5.461 L; 333.3 cu in) M157 twin-turbo V8 M 157 DE 55 AL | 557 PS (410 kW; 549 hp)@5250–5750 | 800 N·m (590 lb·ft)@2000-4500 | 4.2 sec | 21.2000 L/100 km (11.0950 mpg-US) |
| Dyzeliniaivarikliai | ||||||
| E 200 CDI BlueEFFICIENCY | 2010- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA red. | 136 PS (100 kW; 134 hp) | 360 N·m (270 lb·ft)@1600–2600 | 10.2 sec | 4.000 L/100 km (58.80 mpg-US) |
| E 220 CDI BlueEFFICIENCY | 2009- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA | 170 PS (130 kW; 170 hp) | 400 N·m (300 lb·ft)@1400-2800 | 8.7 sec | 4.888 L/100 km (48.12 mpg-US) |
| E 220 CDI BlueEFFICIENCY Edition | 2012- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA | 170 PS (130 kW; 170 hp) | 400 N·m (300 lb·ft)@1400-2800 | 8.7 sec | 4.888 L/100 km (48.12 mpg-US) |
| E 250 CDI BlueEFFICIENCY | 2009- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA | 204 PS (150 kW; 201 hp) | 500 N·m (370 lb·ft)@1600-1800 | 7.7 sec | 5.788 L/100 km (40.64 mpg-US) |
| E 250 CDI 4MATIC BlueEFFICIENCY | 2011- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA | 204 PS (150 kW; 201 hp) | 500 N·m (370 lb·ft)@1600-1800 | 7.9 sec | 5.788 L/100 km (40.64 mpg-US) |
| E 300 BlueTEC HYBRID | 2012- | 2,143 cc (2.143 L; 130.8 cu in) I4 OM 651 DE 22 LA | 231 PS (170 kW; 228 hp) | 750 N·m (550 lb·ft)@- | 7.5 sec | 4.2 L/100 km (56 mpg-US) |
| E 300 CDI BlueEFFICIENCY | 2009-2011 | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 DE 30 LA | 204 PS (150 kW; 201 hp) | 500 N·m (370 lb·ft)@1600-2400 | 7.9 sec | 8.000 L/100 km (29.40 mpg-US) |
| E 300 CDI BlueEFFICIENCY | 2011- | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 LS DE 30 LA | 231 PS (170 kW; 228 hp) | 540 N·m (400 lb·ft) | 6.8 sec | 7.000 L/100 km (33.60 mpg-US) |
| E 350 CDI BlueEFFICIENCY | 2009-2010 | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 DE 30 LA | 231 PS (170 kW; 228 hp) | 540 N·m (400 lb·ft) | 6.8 sec | 7.400 L/100 km (31.79 mpg-US) |
| E 350 CDI 4MATIC BlueEFFICIENCY | 2009-2010 | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 DE 30 LA | 231 PS (170 kW; 228 hp) | 540 N·m (400 lb·ft) | 7.1 sec | 7.400 L/100 km (31.79 mpg-US) |
| E 350 CDI BlueEFFICIENCY | 2010- | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 LS DE 30 LA | 265 PS (195 kW; 261 hp) | 620 N·m (460 lb·ft) | 6.2 sec | 7.400 L/100 km (31.79 mpg-US) |
| E 350 CDI 4MATIC BlueEFFICIENCY | 2010- | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 LS DE 30 LA | 265 PS (195 kW; 261 hp) | 620 N·m (460 lb·ft) | 6.7 sec | 7.400 L/100 km (31.79 mpg-US) |
| E 350 BlueTEC | 2009- | 2,987 cc (2.987 L; 182.3 cu in) V6 OM 642 DE 30 LA | 211 PS (155 kW; 208 hp) | 540 N·m (400 lb·ft) | 7.8 sec | 7.800 L/100 km (30.16 mpg-US) |